Adult Langerhans Cell Histiocytosis with Hepatic and Pulmonary Involvement

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Adult Langerhans Cell Histiocytosis with Hepatic and Pulmonary Involvement

Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of Langerhans cells of unknown etiology. It can involve multiple organ systems with different clinical presentation, which complicates the diagnosis. It can range from isolated to multisystem disease with different prognosis. Although common among children, liver involvement is relatively rare in adults and frequently overlook...

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[Adult pulmonary Langerhans cell histiocytosis].

Adult pulmonary Langerhans’ cell histiocytosis is a rare disorder of unknown aetiology that occurs predominantly in young smokers, with an incidence peak at 20–40 yrs of age. In adults, pulmonary involvement with Langerhans’ cell histiocytosis usually occurs as a single-system disease and is characterised by focal Langerhans’ cell granulomas infiltrating and destroying distal bronchioles. High-...

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[Adult pulmonary Langerhans' cell histiocytosis].

INTRODUCTION Adult pulmonary Langerhans'cell histiocytosis, also referred to as histiocytosis X, is a disorder of unknown etiology which affects preferentially young smokers. The disease is characterized by granulomatous lesions which progressively invade and destroy distal airways, leading to the formation of characteristic cicatricial kystic lesions. Florid granulomas contain numerous Langerh...

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Thyroid involvement in pulmonary Langerhans cell histiocytosis.

A 21-year-old male discovered that his thyroid gland was becoming enlarged in October 2008. Two months later, chest radiography during a routine physical examination revealed an abnormal shadow and he was referred to our hospital for a complete medical examination. He had experienced asthma-like wheezing about once a month for the past 2 years but he was not receiving any medication. He had smo...

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Adult Langerhans cell histiocytosis with pulmonary and colorectoanal involvement: a case report

BACKGROUND Langerhans cell histiocytosis is a rare systemic disease characterized by the abnormal overproduction of histiocytes that tend to infiltrate single or multiple organ systems leading to significant tissue damage. It mainly affects - by order of decreasing frequency - the bone, the skin, the lymph nodes, the liver, and lungs. Gastrointestinal tract involvement is extremely rare in adul...

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ژورنال

عنوان ژورنال: Case Reports in Radiology

سال: 2015

ISSN: 2090-6862,2090-6870

DOI: 10.1155/2015/536328